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Search Results for " reverse transcriptase "

204

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T12715	Reverse transcriptase-IN-1	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Reverse transcriptase-IN-1 是一种二芳基苯并嘧啶类似物，是一种有效的 HIV-1 非核苷类逆转录酶抑制剂，IC50 为 13.7 nM。
T7447	Adefovir	HBV; Reverse Transcriptase; Telomerase	DNA Damage/DNA Repair; Microbiology/Virology
	Adefovir 是一种单磷酸腺苷类似物抗病毒剂，在细胞内转化为 Adefovir diphosphate 后可抑制HBVDNA 聚合酶。它在 HepG2.2.15 细胞系中对HBV 的IC50为 0.7 μM。它对多种病毒(包括HBV 和疱疹病毒)具有良好的抗病毒活性。
T12609	R-10015	LIM Kinase; Reverse Transcriptase	Cell Cycle/Checkpoint; Microbiology/Virology
	R-10015 是一种高效选择性 LIMK 抑制剂，通过结合 ATP 结合口袋阻断 LIMK，抑制人 LIMK1 的 IC50值为 38 nM。它还发挥广谱抗病毒作用，可用于 HIV 感染研究。
T16530	BF738735	Antiviral; PI4K	Immunology/Inflammation; PI3K/Akt/mTOR signaling
	BF738735 是有效的磷脂酰肌醇 4-激酶 IIIβ 抑制剂，IC50为 5.7 nM。
T9223	RO-0335	Reverse Transcriptase	Microbiology/Virology
	RO-0335 是新高效二苯醚非核苷逆转录酶抑制剂。它 (IC50= 1.1 nM) 可以抑制Wt HIV-1病毒，对 92% 的 NNRTI 耐药临床分离株具有保留活性 (IC50<100 nM)。
T16098	Islatravir MK-8591	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Islatravir (MK-8591) 是一种核苷逆转录酶抑制剂，是抗HIV-1药物，对 HIV-1 (WT)，HIV-1 (M184V)，HIV-1 (MDR) 的EC50值分别为 0.068 nM，3.1 nM 和 0.15 nM。
T10133	3'-Azido-3'-deoxy-5-methylcytidine	Antiviral; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	3'-Azido-3'-deoxy-5-methylcytidine 抑制 HIV-1 逆转录酶 (EC50 = 0.06 μM)，是异嗜性鼠白血病相关逆转录病毒 (XMRV, CC50 = 43.5 μM) 的有效抑制剂。
T2330	Rilpivirine TMC278,R278474,利匹韦林,DB08864	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Rilpivirine (R278474) 是一种二芳基嘧啶衍生物和非核苷逆转录酶抑制剂，具有抗 HIV-1 的抗病毒活性，用于治疗 HIV 感染。
T6214	Emtricitabine 恩曲他滨,FTC,Emtriva,BW1592	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Emtricitabine (FTC) 是一种核苷逆转录酶抑制剂，在 PBMC 细胞中的 EC50值为0.01 µM，可研究 HIV 感染。
T5981	2,2'-Anhydrouridine O2,2'-Cyclouridine,2,2'-脱水尿苷,2,2'-Cyclouridine	Antiviral; Reverse Transcriptase	Immunology/Inflammation; Microbiology/Virology
	2,2'-Anhydrouridine (2,2'-Cyclouridine) 有抗肿瘤和抗病毒活性。
T3632	Doravirine 多拉维林,多拉韦林,MK-1439	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Doravirine (MK-1439) 是一种高度特异性的HIV-1非核苷逆转录酶抑制剂，对野生型以及K103N 和Y181C 逆转录酶突变体的IC50值分别为 4.5 nM，5.5 nM 和 6.1 nM。
T72206	Reverse transcriptase-IN-4
	Reverse transcriptase-IN-4 是一种有效的选择性非核苷类逆转录酶 (NNRT) 抑制剂，作用于野生型HIV-1的EC50值为 0.053 μM，作用于HIV-1突变株 E138K 的EC50值为 0.26 μM。
T72203	Reverse transcriptase-IN-3
	Reverse transcriptase-IN-3, 作为一种嘧啶-5-羧酰胺衍生物，主要用于抑制HIV-1。它对HIV-1野生型及其突变型病毒株均展示出高效的抑制活性。
T27154	Dexelvucitabine D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC	Reverse Transcriptase	Microbiology/Virology
	Dexelvucitabine (RVT) 是一种胞苷类似物，一种口服有活性的核苷逆转录酶抑制剂。它是一种 2'-脱氧胞苷抗逆转录病毒剂。它是一种有效的抗 HIV-1病毒剂，这些病毒聚合酶中含有胸苷类似物和/或 M184V 突变。
T1267	Abacavir Epzicom,Ziagen,阿巴卡韦,Abacavir sulfate	Apoptosis; HIV Protease; Reverse Transcriptase	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Abacavir (Ziagen) 是一种核苷类似物逆转录酶抑制剂。
T2578	Didanosine ddI,去羟肌苷,2',3'-Dideoxyinosine	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Didanosine (ddI) 是一种逆转录酶抑制剂，IC50为490nM。
T2551	Etravirine TMC125,依曲韦林,R165335	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Etravirine (R165335) 是一种非核苷逆转录酶抑制剂，具有抗 HIV 的作用。
T2409	Tenofovir alafenamide 替诺福韦艾拉酚胺,替诺福韦,GS-7340	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Tenofovir alafenamide (GS-7340) 是一种核苷酸逆转录酶抑制剂和抗逆转录病毒替诺福韦的新型酯类前药。
T7111	Tenofovir Disoproxil 替诺福韦酯,GS 4331,Bis(POC)-PMPA	HBV; HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Tenofovir Disoproxil (GS 4331) 是一种核苷酸逆转录酶抑制剂，用于治疗 HIV 和慢性乙型肝炎。
T1649	Tenofovir 替诺福韦,泰诺福韦,PMPA,TDF,GS 1278	HBV; HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Tenofovir (GS 1278) 是一种核苷酸逆转录酶抑制剂，可研究 HIV 和慢性乙型肝炎。
T1815	Dapivirine R147681,达匹维林,TMC120	Apoptosis; HIV Protease; Reverse Transcriptase; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
	Dapivirine (R147681) 是一种二芳基嘧啶非核苷类逆转录酶抑制剂。
T0682	Lamivudine GR109714X,BCH-189,拉米夫定	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Lamivudine (BCH-189) 是一种核苷逆转录酶抑制剂，可抑制HIV 逆转录酶1和2 以及乙型肝炎病毒的逆转录酶。
T1675	Adefovir dipivoxil Hepsera,GS 0840,阿德福韦酯,Preveon	Others; HBV; Reverse Transcriptase	Microbiology/Virology; Others
	Adefovir dipivoxil (GS 0840) 是一种腺苷类似物，是核苷逆转录酶抑制剂 Adefovir 的口服前药，具有抗乙型肝炎病毒、疱疹病毒和人类免疫缺陷病毒的活性。
T1595	Nevirapine NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Nevirapine (NVP) 是一种 HIV-1逆转录酶非核苷抑制剂，Ki 值为 270 μM，可用于研究 HIV/AIDS。
T19963	Alizarin Complexone Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid,茜素络合指示剂	Reverse Transcriptase	Microbiology/Virology
	Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) 是 Rous 相关病毒 2 逆转录酶的抑制剂。 Alizarin Complexone 可用作生物研究的钙示踪剂和螯合剂。
T7700	Lersivirine 3-氰基-5-[[3,5-二乙基-1-(2-羟基乙基)-1H-吡唑-4-基]氧基]苯腈,Lersivirine(UK 453061),UK-453061	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Lersivirine (UK-453061) 是非核苷逆转录的抑制剂 (NNRTI)，有效抑制 NNRTI 耐药病毒。它对野生型人类免疫缺陷病毒和临床相关 NNRTI 耐药菌株显示出强大的抗逆转录病毒活性。
T0110	Zalcitabine Dideoxycytidine,ddC,扎西他滨,NSC 606170,Ro 24-2027/000,2',3'-Dideoxycytidine	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Zalcitabine (Dideoxycytidine) 是一种核苷类似物逆转录酶抑制剂，用于HIV 感染相关研究。
T4326	AG 555 Tyrphostin B46,Tyrphostin AG 555	EGFR; Reverse Transcriptase	Angiogenesis; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	AG 555 (Tyrphostin B46)是一种选择性EGFR 的有效抑制剂，可阻断Cdk2活化。它是一种抗逆转录病毒药。
T6367	Abacavir sulfate Abacavir Hemisulfate,硫酸阿巴卡韦,1592U89,ABC sulfate,Ziagen	Apoptosis; HIV Protease; Reverse Transcriptase	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Abacavir sulfate (Ziagen) 是一种核苷类似物逆转录酶抑制剂，可用于 HIV 和 AIDS。
T7282	Tenofovir alafenamide hemifumarate GS-7340 (hemifumarate),Tenofovir alafenamide fumarate,替诺福韦艾拉酚胺富马酸盐	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) 是 HIV 逆转录酶核苷酸抑制剂替诺福韦的口服膦酰胺前药。
T2393	Efavirenz EFV,依非韦伦,DMP 266,依法韦仑,Sustiva,Stocrin,L-743726	HIV Protease; Reverse Transcriptase; Autophagy	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Efavirenz (DMP 266) 是一种人类免疫缺陷病毒 1 非核苷类似物逆转录酶抑制剂。它也是一种野生型HIV-1 RT 抑制剂，Ki 为 2.93 nM，有效抑制 HIV-1 复制，IC95为 1.5 nM。
T1404	Stavudine d4T,Sanilvudine,BMY-27857,NSC 163661,司他夫定	Apoptosis; Nucleoside Antimetabolite/Analog; HIV Protease; NOD-like Receptor (NLR); Reverse Transcriptase; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Stavudine (BMY-27857) 是一种口服活性核苷逆转录酶抑制剂，还抑制线粒体 DNA 的复制，具有抗HIV-1和HIV-2的活性。它降低 NLRP3 炎症小体激活，调节淀粉样 β 自噬，诱导细胞凋亡。
T2409L	Tenofovir Disoproxil Fumarate GS-1278 Disoproxil Fumarate,Tenofovir DF,富马酸替诺福韦酯	HBV; HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) 是一种核苷酸逆转录酶抑制剂，有潜力研究艾滋病和慢性乙型肝炎。
T7212	Delavirdine mesylate U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Delavirdine mesylate (BHAP-U 90152(mesylate)) 是一种口服活性非核苷逆转录酶抑制剂。它抑制 HIV-1 病毒复制，可以用于艾滋病的相关研究。它选择性地抑制 HIV-1 逆转录酶，其选择性超过 DNA 聚合酶 α 和 DNA 聚合酶 δ 。
T14489	Azvudine 4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮,FNC,RO-0622	HCV Protease; HBV; HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Azvudine (FNC) 是一种有效的核苷逆转录酶抑制剂 (NRTI)，对 HIV、HBV 和 HCV 具有抗病毒活性。它抑制耐 NRTI 的病毒株，高效抑制 HIV-1和 HIV-2。
T2160	Suramin Sodium Salt 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060	Apoptosis; Phosphatase; SARS-CoV; Sirtuin; Reverse Transcriptase; Topoisomerase; Parasite	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Suramin Sodium Salt (BAY-205) 是可逆的竞争性蛋白酪氨酸磷酸酶抑制剂。它抑制 IP5K，是抗寄生虫，抗肿瘤和抗血管生成剂。它是sirtuins 的有效抑制剂，也是 SARS-CoV-2 RNA 依赖性 RNA 聚合酶抑制剂。
T9854	HIV-1 inhibitor-6 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) 是一种有效的HIV-1 pre-mRNA 选择性剪接抑制剂，可以阻断HIV 复制。
T21474	Navuridine AZddU,CS 87,CS-87,AzUrd,3'-Azido-2',3'-dideoxyuridine,AZdU,3'-叠氮-2',3'-双脱氧尿苷	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Navuridine (AZdU) 是一种口服活性的 HIV 逆转录酶抑制剂，半衰期相对较短。
T12814	(S)-Tenofovir (S)-替诺福韦,(S)-PMPA,(S)-GS 1278,(S)-TDF	Others	Others
	(S)-Tenofovir ((S)-PMPA) 是Tenofovir 的活性较低的S-对映体，Tenofovir 是一种核苷酸逆转录酶抑制剂。
T7455	4-Chloro-2-(trifluoroacetyl)aniline hydrochloride	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	4-Chloro-2-(trifluoroacetyl)aniline hydrochloride 是 HIV-1 RT（HIV 逆转录酶）的抑制剂。
T1513	Telbivudine NV 02B,L-Thymidine,Epavudine,替比夫定	Others; HBV; Reverse Transcriptase	Microbiology/Virology; Others
	Telbivudine (NV 02B) 是一种乙型肝炎病毒复制的抗病毒抑制剂，是一种具有口服活性的胸腺嘧啶核苷类似物。
T3172	Trovirdine 曲韦定,LY300046	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Trovirdine (LY300046) 是一种硫脲类非核苷类逆转录酶抑制剂。
T31860	Fosdevirine GSK-2248761A,IDX 899,GSK 2248761A,GSK 2248761,GSK-2248761,IDX-12899,GSK2248761,FDV,GSK2248761A	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Fosdevirine (GSK2248761) 是一种具有选择性和高效性的非核苷类逆转录酶 (NNRTI) 抑制剂，具有抗 HIV 活性，可用于研究迟发性癫痫等神经系统相关疾病。
T68103L	Mk-6186 HCl Mk-6186 HCl（1034474-19-5 Free base)	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	MK-6186 HCl，一种新型非核苷类逆转录酶抑制剂，具有抗病毒活性，可用于研究HIV。
T15210	Elsulfavirine Elpida,VM-1500	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Elsulfavirine (VM-1500) 是一种 HIV-1 感染的逆转录酶抑制剂，也是抗 HIV 的新药。
T27260	Emivirine MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Emivirine (MKC-442) 是一种有效和选择性的人类免疫缺陷病毒1型(HIV-1)的非核苷逆转录酶抑制剂。
T68103	MK-6186	Reverse Transcriptase	Microbiology/Virology
	MK-6186 是一种新型非核苷类逆转录酶抑制剂，具有抗病毒活性，可用于研究病毒感染。
T60540	Netivudine
	Netivudine 是一种有效的核苷类逆转录酶抑制剂(NRTIs)，是一种核苷类似物，具有抗水痘带状疱疹病毒活性，可用于治疗人类免疫缺陷病毒(HIV)感染。Netivudine 通过抑制逆转录酶起作用，通过抑制作用减少体内的病毒载量，减缓疾病的进展。
T28255	Opaviraline GW420867X,GW-867,HBY-1293,GW867,GW-420867X	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Opaviraline (GW-420867X) 是一种有效逆转录酶抑制剂，对Human immunodeficiency virus 1具有抑制作用，具有治疗HIV 感染的潜力。
T15436	GSK2838232	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	GSK2838232 是一种新型人类免疫病毒成熟抑制剂，抑制 HIV 逆转录酶活性。

化合物

Reverse transcriptase-IN-1

Cat.No: T12715

Target: HIV Protease

Cat.No: T7447

Target: HBV, Reverse Transcriptase, Telomerase

Cat.No: T12609

Target: LIM Kinase, Reverse Transcriptase

Cat.No: T16530

Target: Antiviral, PI4K

Cat.No: T9223

Target: Reverse Transcriptase

Cat.No: T16098

Synonym: MK-8591

Target: HIV Protease, Reverse Transcriptase

3'-Azido-3'-deoxy-5-methylcytidine

Cat.No: T10133

Target: Antiviral, HIV Protease

Cat.No: T2330

Synonym: TMC278,R278474,利匹韦林,DB08864

Target: HIV Protease, Reverse Transcriptase

Cat.No: T6214

Synonym: 恩曲他滨,FTC,Emtriva,BW1592

Target: HIV Protease, Reverse Transcriptase

2,2'-Anhydrouridine

Cat.No: T5981

Synonym: O2,2'-Cyclouridine,2,2'-脱水尿苷,2,2'-Cyclouridine

Target: Antiviral, Reverse Transcriptase

Cat.No: T3632

Synonym: 多拉维林,多拉韦林,MK-1439

Target: HIV Protease, Reverse Transcriptase

Reverse transcriptase-IN-4

Cat.No: T72206

Reverse transcriptase-IN-3

Cat.No: T72203

Dexelvucitabine

Cat.No: T27154

Synonym: D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC

Target: Reverse Transcriptase

Cat.No: T1267

Synonym: Epzicom,Ziagen,阿巴卡韦,Abacavir sulfate

Target: Apoptosis, HIV Protease, Reverse Transcriptase

Cat.No: T2578

Synonym: ddI,去羟肌苷,2',3'-Dideoxyinosine

Target: HIV Protease, Reverse Transcriptase

Cat.No: T2551

Synonym: TMC125,依曲韦林,R165335

Target: HIV Protease, Reverse Transcriptase

Tenofovir alafenamide

Cat.No: T2409

Synonym: 替诺福韦艾拉酚胺,替诺福韦,GS-7340

Target: HIV Protease, Reverse Transcriptase

Tenofovir Disoproxil

Cat.No: T7111

Synonym: 替诺福韦酯,GS 4331,Bis(POC)-PMPA

Target: HBV, HIV Protease, Reverse Transcriptase

Cat.No: T1649

Synonym: 替诺福韦,泰诺福韦,PMPA,TDF,GS 1278

Target: HBV, HIV Protease, Reverse Transcriptase

Cat.No: T1815

Synonym: R147681,达匹维林,TMC120

Target: Apoptosis, HIV Protease, Reverse Transcriptase, Autophagy

Cat.No: T0682

Synonym: GR109714X,BCH-189,拉米夫定

Target: HIV Protease, Reverse Transcriptase

Adefovir dipivoxil

Cat.No: T1675

Synonym: Hepsera,GS 0840,阿德福韦酯,Preveon

Target: Others, HBV, Reverse Transcriptase

Cat.No: T1595

Synonym: NSC 641530,奈韦拉平,BI-RG 587,奈伟拉平,NVP

Target: HIV Protease, Reverse Transcriptase

Alizarin Complexone

Cat.No: T19963

Synonym: Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid,茜素络合指示剂

Target: Reverse Transcriptase

Cat.No: T7700

Synonym: 3-氰基-5-[[3,5-二乙基-1-(2-羟基乙基)-1H-吡唑-4-基]氧基]苯腈,Lersivirine(UK 453061),UK-453061

Target: HIV Protease, Reverse Transcriptase

Cat.No: T0110

Synonym: Dideoxycytidine,ddC,扎西他滨,NSC 606170,Ro 24-2027/000,2',3'-Dideoxycytidine

Target: HIV Protease, Reverse Transcriptase

Cat.No: T4326

Synonym: Tyrphostin B46,Tyrphostin AG 555

Target: EGFR, Reverse Transcriptase

Abacavir sulfate

Cat.No: T6367

Synonym: Abacavir Hemisulfate,硫酸阿巴卡韦,1592U89,ABC sulfate,Ziagen

Target: Apoptosis, HIV Protease, Reverse Transcriptase

Tenofovir alafenamide hemifumarate

Cat.No: T7282

Synonym: GS-7340 (hemifumarate),Tenofovir alafenamide fumarate,替诺福韦艾拉酚胺富马酸盐

Target: HIV Protease, Reverse Transcriptase

Cat.No: T2393

Synonym: EFV,依非韦伦,DMP 266,依法韦仑,Sustiva,Stocrin,L-743726

Target: HIV Protease, Reverse Transcriptase, Autophagy

Cat.No: T1404

Synonym: d4T,Sanilvudine,BMY-27857,NSC 163661,司他夫定

Target: Apoptosis, Nucleoside Antimetabolite/Analog, HIV Protease, NOD-like Receptor (NLR), Reverse Transcriptase, Autophagy

Tenofovir Disoproxil Fumarate

Cat.No: T2409L

Synonym: GS-1278 Disoproxil Fumarate,Tenofovir DF,富马酸替诺福韦酯

Target: HBV, HIV Protease, Reverse Transcriptase

Delavirdine mesylate

Cat.No: T7212

Synonym: U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)

Target: HIV Protease, Reverse Transcriptase

Cat.No: T14489

Synonym: 4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮,FNC,RO-0622

Target: HCV Protease, HBV, HIV Protease, Reverse Transcriptase

Suramin Sodium Salt

Cat.No: T2160

Synonym: 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060

Target: Apoptosis, Phosphatase, SARS-CoV, Sirtuin, Reverse Transcriptase, Topoisomerase, Parasite

HIV-1 inhibitor-6

Cat.No: T9854

Synonym: 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-

Target: HIV Protease

Cat.No: T21474

Synonym: AZddU,CS 87,CS-87,AzUrd,3'-Azido-2',3'-dideoxyuridine,AZdU,3'-叠氮-2',3'-双脱氧尿苷

Target: HIV Protease

Cat.No: T12814

Synonym: (S)-替诺福韦,(S)-PMPA,(S)-GS 1278,(S)-TDF

Target: Others

4-Chloro-2-(trifluoroacetyl)aniline hydrochloride

Cat.No: T7455

Target: HIV Protease

Cat.No: T1513

Synonym: NV 02B,L-Thymidine,Epavudine,替比夫定

Target: Others, HBV, Reverse Transcriptase

Cat.No: T3172

Synonym: 曲韦定,LY300046

Target: HIV Protease

Cat.No: T31860

Synonym: GSK-2248761A,IDX 899,GSK 2248761A,GSK 2248761,GSK-2248761,IDX-12899,GSK2248761,FDV,GSK2248761A

Target: HIV Protease

Cat.No: T68103L

Synonym: Mk-6186 HCl（1034474-19-5 Free base)

Target: HIV Protease, Reverse Transcriptase

Cat.No: T15210

Synonym: Elpida,VM-1500

Target: HIV Protease

Cat.No: T27260

Synonym: MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302

Target: HIV Protease

Cat.No: T68103

Target: Reverse Transcriptase

Cat.No: T60540

Cat.No: T28255

Synonym: GW420867X,GW-867,HBY-1293,GW867,GW-420867X

Target: HIV Protease

Cat.No: T15436

Target: HIV Protease

Cat. No.	Product Name	Target	Signaling Pathways
T3795	Corilagin	Apoptosis; TLR; Reverse Transcriptase; Antibacterial; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology
	Corilagin 是一种鞣酸，有抑制 RNA 肿瘤病毒逆转录酶的活性。它抑制金黄色葡萄球菌的生长，MIC 为 25 μg/mL。它有抗肿瘤活性，可用于肝癌和卵巢癌。
T6519	Gramine NSC 16892,芦竹碱,Donaxine	Adiponectin receptor; Reverse Transcriptase; Adrenergic Receptor	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Gramine (Donaxine) 是从芦竹中得到的一种生物碱，是脂联素受体激动剂，对 AdipoR2 和 AdipoR1 的 IC50值分别为 3.2 和 4.2 µM。它也是小鼠和人β2-肾上腺素受体激动剂，具有抗肿瘤、抗炎和抗病毒作用。
T2901	Daidzin NPI-031D,大豆苷,Daidzein 7-O-glucoside,Daidzoside,黄豆苷,Daidzein 7-glucoside	Dehydrogenase; Reverse Transcriptase; Mitochondrial Metabolism	Metabolism; Microbiology/Virology
	Daidzin (Daidzoside) 是从大豆中分离出来的一种异黄酮，具有抗氧化、抗癌和抗动脉粥样硬化的活性。
T3578	Pyridoxal phosphate PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate	Reverse Transcriptase; Endogenous Metabolite	Metabolism; Microbiology/Virology
	Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式，可抑制逆转录酶活性，用于研究迟发性运动障碍症。
T6S0923	Hypericin Hypericine,金丝桃素,Cyclosan	Apoptosis; Antiviral; Influenza Virus; Tyrosine Kinases; Antibacterial; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Hypericin (Cyclosan) 是贯叶连翘的提取物，有抗菌、抗病毒、抗肿瘤和抗抑郁作用。
TN1427	Baicalin methyl ester	Anti-infection	Microbiology/Virology
	Baicalin methyl ester 是黄芩苷根的一种成分。
T3730	Methyl gallate NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin,没食子酸甲酯	Reactive Oxygen Species; HIV Protease; Reverse Transcriptase; Antibacterial	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Methyl gallate (Gallincin) 是具有抗氧化，抗癌和抗炎活性的植物酚类。它也可抑制细菌活性。它还具有抗HIV-1和HIV-1酶的抑制活性。
T4S1718	Punicalin	HBV; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Punicalin 是从Punica granatumL. 或Terminalia catappaL. 的叶子中分离的，一种可水解的单宁，具有抗炎活性。它是一种抗乙型肝炎病毒药物。
T9086	Deoxythymidine-5'-triphosphate trisodium dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate(dTTP) trisodium salt) 是四种天然脱氧核苷酸之一，用于通过 DNA 聚合酶和逆转录酶生物合成脱氧核糖核酸。
T2S0605	Liquidambaric lactone	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Liquidambaric lactone 是一种分离自Euonymus grandiflorusWall 中的化合物。
T13796	Nigranoic acid	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.
TN4934	Salaspermic acid	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.
TN5243	Vitexilactone	NADPH-oxidase; HIV Protease; Antifection	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse transcriptase. It has trypanocidal activity, the minimum lethal concentration against epimastigotes
T74196	Inophyllum B
	Inophyllum B ((+)-Inophyllum B) 是一种有效的HIV 逆转录酶 (Reverse Transcriptase) 抑制剂，IC50为 38 nM。Inophyllum B 在体外细胞培养中抑制HIV-1(IC50=1.4 μM)。Inophyllum B 可从非洲大蜗牛Achatina fulica 的丙酮提取物中分离得到。
TN5133	3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone	HIV Protease; Topoisomerase	DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptase. It exhibits cytotoxic activity against P-388 cell lines, it can inhibit DNA topoisomerase IIα activity, which may be responsible for the observed cytotoxicity.

天然产物

Cat.No: T3795

Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy

Cat.No: T6519

Synonym: NSC 16892,芦竹碱,Donaxine

Target: Adiponectin receptor, Reverse Transcriptase, Adrenergic Receptor

Cat.No: T2901

Synonym: NPI-031D,大豆苷,Daidzein 7-O-glucoside,Daidzoside,黄豆苷,Daidzein 7-glucoside

Target: Dehydrogenase, Reverse Transcriptase, Mitochondrial Metabolism

Pyridoxal phosphate

Cat.No: T3578

Synonym: PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Target: Reverse Transcriptase, Endogenous Metabolite

Cat.No: T6S0923

Synonym: Hypericine,金丝桃素,Cyclosan

Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC

Baicalin methyl ester

Cat.No: TN1427

Target: Anti-infection

Cat.No: T3730

Synonym: NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin,没食子酸甲酯

Target: Reactive Oxygen Species, HIV Protease, Reverse Transcriptase, Antibacterial

Cat.No: T4S1718

Target: HBV, HIV Protease

Deoxythymidine-5'-triphosphate trisodium

Cat.No: T9086

Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt

Target: DNA/RNA Synthesis

Liquidambaric lactone

Cat.No: T2S0605

Target: HIV Protease

Cat.No: T13796

Target: HIV Protease

Salaspermic acid

Cat.No: TN4934

Target: HIV Protease

Cat.No: TN5243

Target: NADPH-oxidase, HIV Protease, Antifection

Cat.No: T74196

3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone

Cat.No: TN5133

Target: HIV Protease, Topoisomerase

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